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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: KPNA2 All Species: 46.36
Human Site: S105 Identified Species: 78.46
UniProt: P52292 Number Species: 13
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P52292 NP_002257.1 529 57862 S105 Q A A R K L L S R E K Q P P I
Chimpanzee Pan troglodytes XP_001170686 399 43075
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_861990 529 57923 S105 Q A A R K L L S R E K Q P P I
Cat Felis silvestris
Mouse Mus musculus P52293 529 57910 S105 Q A A R K L L S R E K Q P P I
Rat Rattus norvegicus Q56R16 536 60281 S109 Q K F R K L L S K E P N P P I
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001509792 529 57894 S105 Q A A R K L L S K E K Q P P I
Chicken Gallus gallus Q5ZML1 538 60176 S111 Q K F R K L L S K E P N P P I
Frog Xenopus laevis P52170 522 57670 S102 Q A A R K M L S R E R N P P L
Zebra Danio Brachydanio rerio Q503E9 536 59774 S109 Q K F R K L L S K E P N P P I
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster P52295 522 57803 S98 Q S A R K M L S R E R N P P I
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans Q19969 514 56144 S94 Q Q A R K M L S T D R N P P I
Sea Urchin Strong. purpuratus XP_788859 520 57200 S97 Q T A R R M L S R E R Q P P I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q96321 532 58626 S101 T Q F R K L L S I E R S P P I
Baker's Yeast Sacchar. cerevisiae Q02821 542 60423 S116 V K F R Q I L S R E H R P P I
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 74.8 N.A. 97.7 N.A. 94.5 48.3 N.A. 87.1 46.2 62.9 48.1 N.A. 50.6 N.A. 44.7 60.8
Protein Similarity: 100 75 N.A. 99.2 N.A. 98.1 65.6 N.A. 95.4 64.1 78.6 66 N.A. 68.2 N.A. 63.3 74.8
P-Site Identity: 100 0 N.A. 100 N.A. 100 66.6 N.A. 93.3 66.6 73.3 66.6 N.A. 73.3 N.A. 60 73.3
P-Site Similarity: 100 0 N.A. 100 N.A. 100 73.3 N.A. 100 73.3 93.3 73.3 N.A. 93.3 N.A. 80 93.3
Percent
Protein Identity: N.A. N.A. N.A. 47.3 43.9 N.A.
Protein Similarity: N.A. N.A. N.A. 64.6 61.4 N.A.
P-Site Identity: N.A. N.A. N.A. 60 53.3 N.A.
P-Site Similarity: N.A. N.A. N.A. 66.6 73.3 N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 36 58 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 8 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 86 0 0 0 0 0 % E
% Phe: 0 0 36 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 8 0 0 0 0 % H
% Ile: 0 0 0 0 0 8 0 0 8 0 0 0 0 0 86 % I
% Lys: 0 29 0 0 79 0 0 0 29 0 29 0 0 0 0 % K
% Leu: 0 0 0 0 0 58 93 0 0 0 0 0 0 0 8 % L
% Met: 0 0 0 0 0 29 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 0 0 0 0 0 0 0 0 43 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 22 0 93 93 0 % P
% Gln: 79 15 0 0 8 0 0 0 0 0 0 36 0 0 0 % Q
% Arg: 0 0 0 93 8 0 0 0 50 0 36 8 0 0 0 % R
% Ser: 0 8 0 0 0 0 0 93 0 0 0 8 0 0 0 % S
% Thr: 8 8 0 0 0 0 0 0 8 0 0 0 0 0 0 % T
% Val: 8 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _